Clinical Cytokine, Chemokine, Growth Factor 95-Plex Panel (HD95-Clin)

Description

Unlock comprehensive insights into human cytokines and chemokines with our most popular array, the Cytokine, Chemokine, Growth Factor 95-Plex Panel. This cutting-edge assay enables simultaneous analysis of 95 key biomarkers from a small sample volume, offering a thorough exploration of immune and inflammatory responses.

Eve Diagnostics’ (the division of Eve Technologies) comprehensive cytokine panel provides an in-depth profile of the circulating immune microenvironment underlying the clinical presentation of acute and chronic inflammatory conditions, autoimmune and autoinflammatory diseases. Find a glossary of the 95 analytes contained in this panel here.

Indications:

Use this test to identify relevant therapy targets, determine disease mechanisms, and diagnose or monitor the following conditions associated with immune regulation, inflammation, and cell signaling:

• Autoimmune and Inflammatory Diseases: Assess a wide range of autoimmune and chronic inflammatory conditions such as rheumatoid arthritis, systemic lupus erythematosus (SLE), multiple sclerosis, and inflammatory bowel disease (IBD).
• Infectious Diseases: Evaluate the immune response to bacterial, viral, and fungal infections.
• Cancer: Monitor tumor progression and response to therapy in various cancers, assessing cytokines that are involved in tumor growth, angiogenesis, and immune evasion.
• Allergic and Asthma Conditions: Diagnose and monitor allergic diseases and asthma, where type 2 cytokines play pivotal roles in mediating allergic inflammation and airway hyperreactivity.
• Cardiovascular Diseases: Assess cardiovascular health, including atherosclerosis and heart failure, assessing biomarkers indicating vascular inflammation and remodeling.
• Metabolic and Obesity-Related Disorders: Investigate the role of inflammation in metabolic syndrome, diabetes, and obesity.
• Neurological Disorders: Monitor neuroinflammatory conditions such as multiple sclerosis, Alzheimer’s disease, and neuropathic pain, assessing cytokine profiles indicating neuroinflammation and neuronal damage.
• Bone and Joint Disorders: Evaluate bone and joint diseases such as osteoarthritis and osteoporosis, where the cytokine profile can indicate inflammatory and catabolic processes affecting bone and cartilage.

Eve Technologies distinguishes itself as the only laboratory that has been granted large-panel regulation for the Cytokine, Chemokine, Growth Factor 95-Plex Panel under the Clinical Laboratory Improvement Amendments (CLIA). Our certification as a High Complexity International Laboratory by the Centers for Medicare & Medicaid Services (CMS) (CLIA# 99D2283230) underscores our commitment to rigorous standards.

Key Features:

1. 1.  Comprehensive Biomarker Coverage: Provides a detailed analysis of 95 key biomarkers, including essential biomarkers like IL-6, TNFα, VEGF-A, and IL-10, ensuring a thorough diagnostic approach.
   2. Detailed Report Comments: Our Cytokine, Chemokine, Growth Factor 95-Plex Panel not only provides detailed report comments but also includes cytokine clustering and immune signatures. The assessment of cytokine expression patterns helps identify the type(s) of immunity involved in the patient’s inflammatory response—whether type 1 (Th1), type 2 (Th2), or type 3 (Th17)—and highlights other features such as angiogenesis and hematopoiesis. This comprehensive analysis supports accurate diagnoses and informs relevant treatments.
   3.  CLIA Certified for Clinical Use: As a CLIA certified laboratory, we provide a panel that meets the highest standards of accuracy and reliability for clinical diagnostics.
   4. Versatility: Ideal for identifying therapy targets, understanding disease mechanisms, and studying conditions such as arthritis, macrophage activation syndrome (MAS), Hemophagocytic lymphohistiocytosis (HLH), sepsis, necrotizing fasciitis, meningitis, pneumonia, Kawasaki syndrome, and prolonged or periodic fever. It’s also valuable in investigating ‘cytokine storm’ in COVID-19.
   5. Sample Flexibility: Reference intervals are available for PLASMA-EDTA, SERUM, and CSF samples.
   6. Affordable Assay Services: We offer some of the most affordable assay services available, making advanced diagnostics accessible for clinical applications.
   7. Swift Turnaround Time: We pride ourselves on a rapid turnaround time, with results typically delivered within 5 business days of receiving your specimen and payment.

Why Choose Plasma-EDTA for Accurate Results

For accurate and reliable results, choose plasma-EDTA for all our tests. Plasma, preserved with EDTA, maintains the integrity of your biomarker analysis by preventing clotting and reflecting the true state of the circulating immune environment. Unlike serum, which can release inflammatory factors during clotting, plasma provides a more precise snapshot. Plus, since specific reference intervals for serum haven’t been established for several tests, using plasma-EDTA avoids the risk of sample rejection and ensures the highest quality data.

Trust in plasma-EDTA to deliver the precision you need for impactful insights!

Clinicians: Please check with your State Agency to determine if additional licensure or registration requirements may apply.

! The interpretation of these test results should be correlated with clinical findings and other diagnostic tests. Biomarker levels can vary due to many biological, physiological, and diurnal factors; their clinical significance must be assessed by a qualified healthcare professional. This information is not intended to be used as the sole basis for diagnosis or treatment decisions.